Stability of commercial parenteral lipid emulsions repacking to polypropylene syringes
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چکیده
منابع مشابه
Steroidal Compounds in Commercial Parenteral Lipid Emulsions
Parenteral nutrition lipid emulsions made from various plant oils contain steroidal compounds, called phytosterols. During parenteral administration of lipid emulsions, phytosterols can reach levels in the blood that are many fold higher than during enteral administration. The elevated phytosterol levels have been associated with the development of liver dysfunction and the rare development of ...
متن کاملImmune modulation by parenteral lipid emulsions.
Total parenteral nutrition is the final option for nutritional support of patients with severe intestinal failure. Lipid emulsions constitute the main source of fuel calories and fatty acids (FAs) in parenteral nutrition formulations. However, adverse effects on patient outcomes have been attributed to the use of lipids, mostly in relation to impaired immune defenses and altered inflammatory re...
متن کاملNew parenteral lipid emulsions for clinical use.
Routine use of parenteral lipid emulsions (LE) in clinical practice began in 1961, with the development of soybean oil (SO) - based LE. Although clinically safe, experimental reports indicated that SO-based LE could exert a negative influence on immunological functions. Those findings were related to its absolute and relative excess of omega-6 polyunsaturated fatty acids (PUFA) and the low amou...
متن کاملStability of cefazolin sodium in polypropylene syringes and polyvinylchloride minibags.
BACKGROUND Cefazolin is a semisynthetic penicillin derivative with a narrow spectrum of activity covering some gram-positive organisms and a few gram-negative aerobic bacteria. OBJECTIVE To determine the physical and chemical stability of cefazolin sodium reconstituted with sterile water for injection and stored in polypropylene syringes or diluted with either 5% dextrose in water (D5W) or 0....
متن کاملBenefits of Parenteral Lipid Emulsions in Acute Respiratory Failure
Lipid emulsions in parenteral nutrition can interfere with pulmonary functions in patients displaying anomalies of the ventilation-perfusion ratio. The underlying mechanisms are unknown, but involve modifications of the production of vasoconstrictor and vasodilator eicosanoids as an effect of lipid infusion. Preferential synthesis of one or other of the eicosanoid types depends on the rate of a...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2019
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0214451